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HEREDITARY BILATERAL RETINOBLASTOMA, PINEALOMA AND NORMAL CHROMOSOMES
Author(s) -
EHLERS NIELS,
KAAE SIGVARD,
RASMUSSEN KIRSTEN,
RATJEN ERLING
Publication year - 1983
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1983.tb01465.x
Subject(s) - retinoblastoma , pinealoma , chromosome , retina , biology , pathology , medicine , genetics , neuroscience , gene
We report a boy with bilateral, familial retinoblastoma recognized at the age of 3 months. At the age of 2 1/2 years the patient developed a tumour in the pineal region. Both tumours were successfully treated by radiation. The chromosomes were normal when examined by the prophase technique, in particular there was no deletion of band q 14 of chromosome 13. We consider the simultaneous occurrence of retinoblastoma and pinealoma as more then a pure coincidence, probably a consequence of a generally increased susceptibility to cancer and of the histogenetic similarities of retina and pineal body.