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EARLY EFFECTS OF SODIUM IODATE ON THE SLOW OFF‐EFFECTS, PARTICULARLY THE h‐WAVE, AND ON THE c‐WAVE OF THE DC RECORDED ELECTRORETINOGRAM IN RABBIT
Author(s) -
WELINDER E.,
TEXTORIUS O.
Publication year - 1982
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1982.tb08386.x
Subject(s) - iodate , polarity (international relations) , chemistry , sodium , endocrinology , medicine , iodine , biochemistry , organic chemistry , cell
The early effects of intravenously administered sodium iodate (NaIO 3 ) on the slow, negative ‘off‐effect’, the h ‐wave, and on the slow, positive ‘on‐effect’, the c ‐wave, of the DC recorded electroretinogram were studied in 8 rabbits. Both the h ‐ and c ‐waves disappeared gradually after NaIO 3 administration and were replaced by potentials of opposite polarity. These results strongly support the assumption that the h ‐wave originates in the pigment epithelium and represents the reversal of events underlying the c ‐wave. The slow, positive ‘off‐effect’, the g ‐wave, elicited by ‘dark flashes’ was seen to pass into the potential replacing the h ‐wave after NaIO 3 treatment.