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THE EFFECT OF PRENALTEROL, AN ADRENERGIC BETA 1 ‐AGONIST, ON INTRAOCULAR PRESSURE, HEART RATE, AND BLOOD PRESSURE
Author(s) -
ALM ALBERT,
TÖRNQUIST PER,
WICKSTRÖM CARL PETER
Publication year - 1981
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1981.tb05763.x
Subject(s) - medicine , blood pressure , placebo , intraocular pressure , agonist , heart rate , adrenergic agonist , anesthesia , adrenergic receptor , cardiology , receptor , ophthalmology , alternative medicine , pathology
The effects on the intraocular pressure (IOP), systolic and diastolic blood pressures and heart rate of the beta 1 ‐adrenergic agonist prenalterol was determined in a double‐masked, randomized study on healthy volunteers. A solution of placebo or 5 mg prenalterol was administered orally. No effect on IOP was observed while prenalterol had significant cardiovascular effects compared to placebo. Thus the present study does not support the assumption that betai‐adrenergic receptors are involved in the regulation of IOP.