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QUANTITATIVE STUDY OF CONJUNCTIVAL CYTOLOGY IN RELATION TO CORNEAL GRAFTING
Author(s) -
NORN M.S.
Publication year - 1981
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1981.tb05753.x
Subject(s) - neutrophilia , medicine , eosinophilia , cytology , lymphocytosis , conjunctiva , leukocytosis , ophthalmology , pathology , surgery , immunology
Using the quantitative pipette method we could follow the cell contents of the conjunctival fluid in 28 patients subjected to 34 corneal graftings, a total of 308 samples, of which 85 were followed for more than 3 months post‐operatively. All (100%) showed initial neutrophilia (more than 100 neutrophils/φ mm 2 ) within the first 48 h. The percentage decreased gradually to 50 about the 13th to 15th day. The intensity of the reaction seemed to be of no prognostic significance. Late neutrophilia only occurred in association with complications (abscess in the corneal graft, panophthalmia, bacterial conjunctivitis, late graft rejection). Late lymphocytosis was only observed in relation to late rejection (4 grafts with 8 rejection periods. Four other grafts subject to rejection showed neutrophilia or normal cytology). Eosinophilia was infrequently seen at an early stage in 35% of all grafts, even in cases which remained uncomplicated. The method is of use in the differential diagnosis of graft complications.