Premium
TIMOLOL VERSUS PILOCARPINE SEPARATELY OR COMBINED WITH ACETAZOLAMIDE‐EFFECTS ON INTRAOCULAR PRESSURE
Author(s) -
CALISSENDORFF B.,
MARÉN N.,
WETTRELL K.,
ÖSTBERG A.
Publication year - 1980
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1980.tb08304.x
Subject(s) - acetazolamide , timolol , pilocarpine , intraocular pressure , medicine , glaucoma , ophthalmology , ocular hypertension , anesthesia , psychiatry , epilepsy
Fifty‐eight patients with intraocular hypertension or primary open angle glaucoma participated in a double masked randomized study. Timolol in concentrations 0.25% and 0.5% was compared with 1, 2, or 4% pilocarpine. Acetazolamide (250 mg × 3) was added if intraocular pressure (IOP) was uncontrolled with the highest concentrations tested. No statistical difference was found in hypotensive effect between pilocarpine and timolol neither on ocular hypertensions nor glaucomas. The additive hypotensive effect of acetazolamide was the same for both substances. Once a day administration of timolol was sufficient in 17 of 20 cases controlled merely by topical administration.