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ADVANCED RETINOBLASTOMA IN MALAYSIAN CHILDREN
Author(s) -
SINNIAH D.,
NARASIMHA G.,
PRATHAP K.
Publication year - 1980
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1980.tb06696.x
Subject(s) - enucleation , kuala lumpur , retinoblastoma , medicine , vincristine , cyclophosphamide , pediatrics , radiation therapy , disease , surgery , chemotherapy , gene , biochemistry , marketing , business , chemistry
Twenty children with retinoblastoma are reviewed who were treated at the University Hospital, Kuala Lumpur over a 10‐year‐period. They constitute 6.6% of childhood malignancies and without exception all presented with advanced disease. Hereditary cases were notably absent in the the series probably because past cases have almost invariably succumbed without an opportunity to transmit the gene. With enucleation and radiotherapy six of the patients have survived from 2 to 12 years. The addition of vincristine and cyclophosphamide has not been associated with improved survival.