Premium
ON THE SIGNIFICANCE OF A LOW ENDOTHELIAL CELL DENSITY IN FUCHS‘ ENDOTHELIAL DYSTROPHY. A SPECULAR MICROSCOPIC STUDY
Author(s) -
OLSEN THOMAS
Publication year - 1980
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1980.tb04572.x
Subject(s) - dystrophy , endothelial stem cell , specular reflection , ophthalmology , medicine , pathology , anatomy , chemistry , optics , physics , biochemistry , in vitro
In order to verify whether a low endothelial cell density is a primary event in Fuchs' endothelial dystrophy, a specular microscopic examination was attempted in 20 patients with Fuchs' dystrophy. Most of these patients had previously undergone cataract extraction. In five patients only, was it possible in places to observe endothelial cellular outline to such an extent that the cell density could be estimated. The resulting estimates ranged from 715 to 2380 cells/mm 2 and were not, as a group, found to be lower than in a control group of aphakic subjects. This finding is evidence against the view that Fuchs' endothelial dystrophy is a low cell density syndrome.