Premium
CHORIORETINITIS OF THE NEWBORN WITH HERPES SIMPLEX VIRUS TYPE 1
Author(s) -
REERSTED PER,
HANSEN BENTE
Publication year - 1979
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1979.tb00543.x
Subject(s) - chorioretinitis , herpes simplex virus , medicine , virology , virus , lesion , hsl and hsv , transmission (telecommunications) , antibody , simplexvirus , herpesviridae , immunology , viral disease , pathology , ophthalmology , electrical engineering , engineering
A disseminated herpes simplex virus (HSV) infection involving the central nervous system and accompanied by chorioretinitis in a 3–week‐old girl is described. The aetiologic diagnosis was established on the basis of virus isolated from skin vesicles, and a significant rise in complement fixing antibodies to HSV type 1. The mode of transmission of the virus to the infant apparently was direct contact with an oral lesion in the mother, that was present at the time of delivery. The patient survived but became blind and microcephalic, with severe neurological sequelae. The virus isolated was identified as HSV type 1, which is an infrequent finding in herpetic chorioretinitis of the newborn.