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VITREO‐SCLERAL FLUID TRANSFER IN THE RABBIT
Author(s) -
MOSELEY M.,
JOHNSON N. F.,
FOULDS W. S.
Publication year - 1978
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1978.tb06641.x
Subject(s) - sclera , rabbit (cipher) , xenon , tracer , diffusion , chemistry , materials science , biomedical engineering , ophthalmology , medicine , physics , thermodynamics , mathematics , statistics , organic chemistry , nuclear physics
Experiments were carried out to see whether a radioactive tracer placed in the vitreous of a rabbit eye could be detected on the sclera. A solution of Xenon‐133 dissolved in saline was injected into the vitreous of six rabbits and collecting tubes containing activated charcoal were placed on the sclera. The presence of Xenon in these tubes confirmed that vitreo‐scleral transfer had occurred It was calculated that on average, 2% of the Xenon had appeared over the whole sclera. A mathematical analysis of the shape of the activity curve of the tracer on the sclera revealed that its appearance was probably due to diffusion across the outer layers of the eye