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A DOUBLE‐BLIND STUDY ON THE INFLUENCE OF TRANEXAMIC ACID ON THE INTRAOCULAR PRESSURE AND THE CENTRAL CORNEAL THICKNESS AFTER TRABECULECTOMY FOR GLAUCOMA SIMPLEX
Author(s) -
BRAMSEN THORKILD
Publication year - 1978
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1978.tb03819.x
Subject(s) - tranexamic acid , trabeculectomy , intraocular pressure , glaucoma , medicine , ophthalmology , antifibrinolytic , aqueous humour , aqueous humor , surgery , blood loss
The influence of tranexamic acid on the intraocular pressure and central corneal thickness has been examined by means of a double‐blind trial in patients with glaucoma simplex. The material comprised 28 patients (14 pairs) who had all been operated on for glaucoma in one eye by trabeculectomy. Tranexamic acid was found not to influence the intraocular pressure, neither in the operated eye nor in the opposite eye. The possible antifibrinolytic effect on the outflow of the aqueous humour is discussed. As in previous studies an effect of tranexamic acid on the central corneal thickness was found in both the operated and in the non‐operated eye. A possible mechanism behind this is discussed.