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TIMOLOL
Author(s) -
NIELSEN NIELS VESTI
Publication year - 1978
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1978.tb01363.x
Subject(s) - timolol , acetazolamide , medicine , intraocular pressure , ophthalmology , anesthesia , epinephrine
In 43 persons with increased intraocular pressure (IOP) Timolol maleate eye drops (0.25 % and 0.5 %) were used as a single and combined treatment. A significant decrease in IOP was noticed in 34 persons ( P < 0.001) initially. No diminished effect of treatment was apparent after 9 weeks in 34 subjects or after 15 weeks in 23 subjects with Timolol alone. In nine persons with high IOP, Timolol had a significant ( P < 0.001) but insufficient lowering effect. Epinephrine (1 %) and acetazolamide appeared to have an additive effect in these cases. No serious local or systemic adverse effects were discovered.