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FLUORESCEIN AND INDOCYANINE GREEN FLUORESCENCE ANGIOGRAPHY IN STUDY OF AFFECTED MALES AND IN FEMALE CARRIERS WITH CHOROIDERMIA
Author(s) -
FORSIUS HENRIK,
HYVÄRINEN LEA,
NIEMINEN HEIKKI,
FLOWER ROBERT
Publication year - 1977
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1977.tb06123.x
Subject(s) - indocyanine green , retinal pigment epithelium , medicine , fundus (uterus) , fluorescein angiography , ophthalmology , fluorescein , macular degeneration , indocyanine green angiography , choroid , angiography , epithelium , retina , pathology , surgery , retinal , fluorescence , biology , optics , physics , neuroscience
26 males and 13 female carriers of different ages with choroideremia of varying severity were investigated using sodium fluorescein (FAG) and/or indocyanine green (ICG) fluorescence angiography. Females with minor changes present in pigment epithelium may stay unchanged throughout life or gradually develop into a more advanced stage resembling the fundus picture of severely affected males. In moderately affected females there is a patchy degeneration of pigment epithelium in the macula. Peripapillary degeneration is seen also in indocyanine green fluorescence angiograms. In males, atrophic areas and the remaining choriocapillaris are clearly demonstrated in FAG and less well visible in ICG angiograms. ICG angiograms show choroidal vessels more clearly in cases where the pigment epithelium and the choriocapillaris are still present. In advanced cases in males and females, the choroidal blood circulation is slow.