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EFFECTS OF OPHTHALMIC VEHICLES ON THE STABILITY OF THE PRECORNEAL FILM
Author(s) -
NORN MOGENS S.,
OPAUSZKI ANNA
Publication year - 1977
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1977.tb06092.x
Subject(s) - benzalkonium chloride , polyvinyl alcohol , anhydrous , methyl cellulose , chromatography , chemistry , silicone oil , polyethylene glycol , materials science , cellulose , organic chemistry
The break up time (B. U. T.) of the precorneal film has been studied before and after application of 34 different vehicles. The material examined comprised 646 eyes. Maximum increase of the B. U. T. was obtained with 2% methyl cellulose (four times) and 10% polyvinyl alcohol (seven times). These vehicles in the usually employed concentrations, fat‐free ointment (polyethylene glycol), acetyl cysteine and polysaccharide (dextran) affected a less pronounced prolongation. The B. U. T. was reduced four or five times by fatty, anhydrous ointments and by silicone oil, about two or three times by emulsions and oils, and twice by 0.01% benzalkonium chloride. The clinical significance of the B. U. T. alterations is discussed.