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MAST CELLS AND PTERYGIUM
Author(s) -
RATNAKAR K. S.,
GOSWAMY V.,
AGARWAL L. P.
Publication year - 1976
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1976.tb01265.x
Subject(s) - metachromasia , conjunctiva , pathology , mast cell , pterygium , toluidine , lesion , medicine , anatomy , chemistry , ophthalmology , staining , immunology
A total of thirty pterygia were studied for mast cells using metachromatic dye (toluidine blue) together with routine histological stains. On microscopic examination, the lesion was differentiated and classified into angiomatous, fibrous and mixed varieties based on the vascular and collagenous components. The mast cell counts were undertaken in all types and were found to have significant correlation with the morphological types when compared to normal conjunctiva. 15.1 ± 3.1, 22.7 ± 3.8, 9.5 ± 3.2 mast cells per mm 2 were found in the angiomatous, mixed and fibrous types respectively. In the control material, the mast cell count was 12.4 ± 2.3 per mm 2 . The results are discussed. It is believed that mast cells are actively involved in the genesis and progress of pterygium.