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MALIGNANT MELANOMA OF THE CHOROID IN AN 11‐MONTH‐OLD INFANT
Author(s) -
FLEDELIUS HANS,
LAND ANNA MARIE
Publication year - 1975
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1975.tb01150.x
Subject(s) - choroid , melanin , melanoma , melanosis , medicine , danish , dermatology , pathology , biology , cancer research , neuroscience , retina , linguistics , genetics , philosophy
A malignant melanoma of the choroid was observed in an 11‐month‐old fair‐skinned Danish boy — one of the youngest cases ever published. There was no evidence of pre‐existing melanosis of eyes or skin. The tumour showed histopathologically a typical “adult” pattern and was classified as a mixed tumour. The melanin content was marked. In some earlier reports on uveal tumours within the first year of life, pigmentation was sparse or lacking; a hypothesis has therefore previously been advanced: That melanomas are unable to produce melanin so early in life. The present case renders proof against this hypothesis.