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FLUOREXON VITAL STAINING OF CORNEA AND CONJUNCTIVA
Author(s) -
NORN M. S.
Publication year - 1973
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1973.tb08259.x
Subject(s) - rose bengal , staining , fluorescein , fluorescent staining , conjunctiva , cornea , slit lamp , pathology , vital stain , chemistry , fluorescence , ophthalmology , medicine , optics , physics , organic chemistry
Fluorexon is a large‐molecular fluorescein derivative, which may be of use in the fitting of soft contact lenses. Its staining properties have been assessed by slit lamp examination of 146 eyes and microscopy of 40 preparations. The dye effected partly fluorescent and partly nonfluorescent staining. Both components were best seen in cobalt‐filtered light. The fluorescent component was noticed in the presence of epithelial defects, corresponding to the conditions seen after staining with fluorescein, though of a much lower grade. The non‐fluorescent component represented staining of dead or degenerate cells, thus having the same properties as rose bengal, though likewise staining less intensely. Using fluorexon instead of fluorescein and rose bengal will obscure information concerning various important facts (punctate fluorescein staining, epithelial blebs, epithelial defect of dendritic pattern, mild keratoconjunctivitis sicca, etc.).