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PEROXIDASE DIFFUSION IN THE RABBIT CILIARY BODY IN EXPERIMENTAL UVEITIS
Author(s) -
PEDERSEN OLAV ØYVIND
Publication year - 1973
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1973.tb06057.x
Subject(s) - peroxidase , horseradish peroxidase , ciliary body , uveitis , chemistry , ciliary processes , infiltration (hvac) , diffusion , ophthalmology , pathology , medicine , enzyme , biochemistry , materials science , physics , composite material , thermodynamics
Experimental uveitis has been produced in albino rabbits by injection of human serum albumin into the vitreous body. To study the blood‐aqueous barrier in the ciliary body in experimental uveitis, horseradish peroxidase has been used as a cytochemical tracer by light microscopy. After intravenous injection of peroxidase, it gained ready access to the posterior chamber in the uveitis eyes. The diffusion barrier to peroxidase in the ciliary epithelium was broken in localized areas. At these sites, heavy infiltration of leukocytes was found, and a continuous epithelial lining was apparently lacking. Outside these areas the diffusion barrier to peroxidase was found intact.