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PERSISTENT HYPERPLASTIC PRIMARY VITREOUS IN NON‐IDENTICAL TWINS
Author(s) -
WANG M. K.,
PHILLIPS C. I.
Publication year - 1973
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1973.tb06022.x
Subject(s) - clearance , medicine , sibling , identical twins , ophthalmology , pediatrics , psychology , developmental psychology , urology
Non‐identical twin females presented because one had a spontaneous left hyphaema. When this cleared, a retrolental vascularised white mass, presumably persistent hyperplastic primary vitreous (PHPV), was seen in the left eye. This eye was very slightly smaller than the right. The parents had noticed that her twin had a left convergent squint; the diagnosis of PHPV was also made in this twin's left eye which was also smaller than the right. An older male sibling is normal. The parents are not consanguineous. A recessive gene is the likeliest explanation, but an intra‐uterine environmental factor such as infection is a definite possibility. (No other sibships with or cases of persistent hyperplastic primary vitreous with affected first degree relatives seem to have been reported.)