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CONGENITAL DISTICHIASIS
Author(s) -
MUSTONEN EILA
Publication year - 1972
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1972.tb05990.x
Subject(s) - penetrance , consanguinity , medicine , family history , ophthalmology , biology , surgery , pediatrics , genetics , gene , phenotype
Three separate families were examined in three generations after one case of distichiasis had, by chance, been found in every family. No history of consanguinity was found in these families. In the first family 48 members were examined, 45 of them personally by the writer. Nine subjects, most of them myopic, were found to have distichiasis. In the second family 39 members were personally examined and no other case of distichiasis was found. The one patient was myopic. The third family with 7 examined members had also only one case of distichiasis. This patient was hyperopic. Histopathology was studied after two patients from the first family had been operated because of irritation of the eyes by aberrant lashes. The mode of inheritance seemed to be autosoma1 dominant with quite high penetrance. Of the total 11 cases, 8 were myopic.