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CHEMICAL AND MECHANICAL DISSOLUTION OF HUMAN SENILE CATARACTS IN VITRO
Author(s) -
KLEIN JAMES,
COTLIER EDWARD
Publication year - 1972
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1972.tb03781.x
Subject(s) - cataracts , in vitro , senile cataract , dissolution , ophthalmology , chemistry , medicine , biochemistry , organic chemistry
The effects of mechanical and chemical dissolution on 100 human senile cataracts were tested in vitro . Senile cataracts obtained immediately after surgical removal were grouped in three classes according to transparency, color and hardness (resistance to perforation). Dissolution of the lenses by various chemicals during push‐pull aspirations was tested by weighing and by photography of cataracts before and after treatment. Mechanical forces deaggregated senile cataracts depending on the specific cataract types. Guanidine hydrochloride in 1 Molar concentration accelerated the rate of cataract breakdown in vitro .