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LEBER's DISEASE III
Author(s) -
SEEDORFF TOVE
Publication year - 1969
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.1969.tb05606.x
Subject(s) - danish , limit (mathematics) , value (mathematics) , disease , demography , medicine , statistics , mathematics , sociology , philosophy , linguistics , mathematical analysis
Summary This paper reports part of a study aiming at completing previously published Danish families with Leber's disease and thereby at contributing a share in the discussion concerning the carrier rate. The family in question comprises 59 persons distributed over 9 generations. There is a high percentage of childless women in this family. In the discussion of the value of the pedigree, it is pointed out that owing to the sparse reproduction it is hardly possible to establish the carrier rate with a reasonable limit of error in such a pedigree in spite of its considerable size.