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In vitro antimicrobial effects of commercially available mouth‐wetting agents
Author(s) -
Güneri Pelin,
Alpöz Esin,
Epstein Joel B.,
Çankaya Hülya,
Ates Mustafa
Publication year - 2011
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/j.1754-4505.2011.00194.x
Subject(s) - antimicrobial , streptococcus mutans , lactobacillus acidophilus , candida albicans , agar diffusion test , saliva , medicine , agar , microbiology and biotechnology , in vitro , active ingredient , food science , bacteria , antibacterial activity , chemistry , pharmacology , biology , probiotic , biochemistry , genetics
Products have been developed to provide palliation for persons with dry mouth. In addition to mouth‐wetting agents, some products incorporate antimicrobial constituents with the goal of improving oral microbial defenses. The aim of this in vitro study was to investigate the potential antimicrobial and antifungal effects of two commercially available saliva substitutes on Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans by using the agar‐well diffusion method. Antimicrobial activity as measured by the size of the inhibition zone growth for S. mutans and L. acidophilus was observed only with Biotene Dry Mouth Oral Rinse ® and BioXtra ® gel. The zone of inhibition of Biotene Dry Mouth Oral Rinse was larger than that of BioXtra gel ( p = 0.00, p < 0.01). No anticandidal effect was seen with any of the test products. The pH of the preparations, the variations between the amount of active ingredients within the products, and the potential antimicrobial effects of inactive ingredients should be investigated to determine the factors that impacted microbial inhibition.