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Chronic craniofacial dematiaceous fungal infection: A case report
Author(s) -
Shetty Kishore,
Giannini Peter,
Achong Ronald
Publication year - 2006
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/j.1754-4505.2006.tb01717.x
Subject(s) - itraconazole , medicine , curvularia , ketoconazole , dermatology , amphotericin b , terbinafine , miconazole , sinusitis , antifungal , microbiology and biotechnology , immunology , biology , aspergillus
Curvularia is a saprobic dematiaceous mold that has been associated with a wide spectrum of human infection. In non‐immunosuppressed patients, infections frequently involve the paranasal sinus, skin, and soft tissue, whereas systemic dissemination and endocarditis are extremely rare. The optimal antifungal therapy for Curvularia infection is not known, and responses to treatment with amphotericin B, miconazole, ketoconazole, terbinafine, and itraconazole have been reported. We describe a patient with an invasive dematiaceous fungal sinusitis who was immunocompetent and was infected with Curvularia . The patient was successfully treated with oral itraconazole by otolaryngology and the infectious disease service.