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Amlodipine‐induced gingival overgrowth: periodontal responses to stopping and restarting the drug
Author(s) -
Morisaki Ichijiro,
Dol Shizuka,
Ueda Katsura,
Amano Atsuo,
Hayashi Mikiko,
Mihara Joji
Publication year - 2001
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/j.1754-4505.2001.tb00226.x
Subject(s) - medicine , amlodipine , dentistry , drug , gingival and periodontal pocket , periodontitis , pharmacology , blood pressure
A case history of a woman with gingival overgrowth (GO) induced by amlodipine is presented. A 49‐year‐old Japanese woman, who was taking amlodipine, had gingival overgrowth and swelling on examination. No specific periodontal treatment was provided to the patient for the GO; however, the amlodipine was replaced with an ACE inhibitor after consultation with her medical practitioner. Within two months, the suspension of amlodipine resulted in a significant improvement in her periodontal condition. Failure to control the hypertension caused the physician to re‐prescribe amlodipine. After three months, the gingival overgrowth returned; however, its severity was less when compared with the original periodontal condition, due to reduction in drug dose and periodontal therapy. This experience suggests that temporary suspension of a drug which can induce GO can improve the periodontal condition without the aid of surgical treatment.