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Idiopathic myelofibrosis: dental treatment considerations
Author(s) -
Steelman Robert,
Holmes Douglas,
Cranston Roberta,
Cupp Dolly
Publication year - 1991
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/j.1754-4505.1991.tb00818.x
Subject(s) - medicine , myelofibrosis , anemia , bone marrow , population , extramedullary hematopoiesis , myeloproliferative disorders , pediatrics , surgery , haematopoiesis , stem cell , biology , genetics , environmental health
Idiopathic myelofibrosis is a myeloproliferative disorder of unknown origin. The bone marrow becomes fibrotic with an associated decrease in hematopoiesis resulting in anemia, bleeding problems, splenomegaly, and other secondary abnormalities. Although idiopathic myelofibrosis is usually diagnosed in middle age, there have been a few reports of the disorder in the pediatric population. This case report documents dental treatment considerations in a 6‐year‐old female with idiopathic myelofibrosis, severe anemia, and abnormal blood coagulation studies. The patient was successfully treated in a hospital after medical consultation, transfusion of packed red blood cells, and administration of prophylactic antibiotics. Local hemostatic measures following multiple extractions of carious teeth controlled bleeding. No postoperative sequelae occurred.