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Clinical trials in special care populations: some methodological issues requiring attention with limited group sizes
Author(s) -
Heifetz Stanley B.
Publication year - 1991
Publication title -
special care in dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.328
H-Index - 41
eISSN - 1754-4505
pISSN - 0275-1879
DOI - 10.1111/j.1754-4505.1991.tb00811.x
Subject(s) - medicine , plague (disease) , clinical trial , family medicine , pathology
As many researchers have experienced, studying special patient populations can be particularly challenging. The problem of heterogeneity of the experimental material that can plague any research design becomes even more prominent when studying special patients because of limited group sizes. Dr. Stanley B. Heifetz, former acting chief of clinical trials at NIDR, offers SCD readers some guidelines to avoid the pitfalls of inadequate research methods