Open AccessVaccination against hepatitis A and B in persons subject to homelessness in inner Sydney: vaccine acceptance, completion rates and immunogenicity
Author(s) -
Poulos Roslyn G.,
Ferson Mark J.,
Orr Karen J.,
McCarthy Michele A.,
Botham Susan J.,
Stern Jerome M.,
Lucey Adrienne
Publication year - 2010
Publication title -
australian and new zealand journal of public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.946
H-Index - 76
eISSN - 1753-6405
pISSN - 1326-0200
DOI - 10.1111/j.1753-6405.2010.00496.x
Subject(s) - vaccination , medicine , serology , vaccination schedule , hepatitis b , immunogenicity , population , family medicine , disadvantaged , hepatitis a , immunology , environmental health , hepatitis , immunization , antibody , political science , law
Objectives:To determine acceptance, completion rates and immunogenicity of the standard vaccination schedule for hepatitis A (HAV) and B (HBV) in persons subject to homelessness.Methods:A convenience sample of clients (n=201) attending a medical clinic for homeless and disadvantaged persons in Sydney was enrolled. Serological screening for HAV and HBV was undertaken. An appropriate vaccination program was instituted. Post‐vaccination serology determined serological response.Results:Although many clients had serological evidence of past infection, at least 138 (69%) clients had the potential to benefit from vaccination. For hepatitis A and B vaccinations, completion rates were 73% (73 of 100 clients) and 75% (69 of 92 clients), respectively; after vaccination, protective antibody was found in 98.2% (56 of 57) and 72% (36 of 50) of clients, respectively.Conclusion:A successful vaccination program can be mounted with a vulnerable population. We consider a clinic with a well‐established history of acceptance and utilisation by the target group; a low staff turnover and regular clientele; inclusion of vaccination as part of routine client care; and counselling (part of pre‐ and post‐serological testing) essential components in achieving good vaccination completion rates.