Open AccessEpidemiology of Type 2 diabetes mellitus in Aleppo, Syria
Author(s) -
ALBACHE Nizar,
AL ALI Radwan,
RASTAM Samer,
FOUAD Fouad M.,
MZAYEK Fawaz,
MAZIAK Wasim
Publication year - 2010
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/j.1753-0407.2009.00063.x
Subject(s) - medicine , type 2 diabetes mellitus , body mass index , diabetes mellitus , family history , epidemiology , population , waist , waist–hip ratio , demography , endocrinology , environmental health , sociology
Abstract Background: Type 2 diabetes mellitus (T2DM) is considerable public health problem, but data on the prevalence and correlates of T2DM in Syria are scarce. The aim of the present study was to establish reliable estimates of the prevalence of T2DM in Syria. Methods: A cross‐sectional, population‐based survey was conducted in Aleppo, Syria (population 2.5 million), in 2006. The study was conducted on a random sample of 1168 subjects ≥25 years of age (47.7% men; mean age 44.7 ± 12.7 years). Information regarding a personal history of diabetes and other risk factors was collected, followed by measurement of weight, height, and the waist:hip ratio (WHR). Of the 1168 participants, 806 provided fasting blood samples that were analyzed for fasting plasma glucose (FPG) and HbA1c. Results: The prevalence of T2DM based on FPG ≥126 mg/dL and HbA1c ≥6.5% was 15.6% (11.2% self‐reported; 5.0% diagnosed) and 14.8%, respectively. The prevalence of impaired fasting glucose (FPG ≥110 and <126 mg/dL) was 8.6%. There was a significant positive association between T2DM and age, WHR, a family history of T2DM, and body mass index (BMI) and an inverse association between T2DM and physical activity ( P < 0.01 for all). Multivariate analysis showed that age, BMI, WHR, and a family history of T2DM were the most important factors associated with T2DM. Only 16.7% of treated cases of T2DM were under control (i.e. HbA1c <7%). Conclusions: Based on the results obtained in our sample, T2DM is widespread in Syria. Many of those with T2DM are unaware of their disease and most have unsatisfactory control of their disease.