Open AccessConcomitant obstructive sleep apnea and chronic obstructive pulmonary disease: study design – the OLIN OSAS‐COPD study
Author(s) -
Larsson L.G.,
Lindberg A.
Publication year - 2008
Publication title -
the clinical respiratory journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.789
H-Index - 33
eISSN - 1752-699X
pISSN - 1752-6981
DOI - 10.1111/j.1752-699x.2008.00094.x
Subject(s) - medicine , spirometry , copd , obstructive sleep apnea , concomitant , physical therapy , obstructive lung disease , quality of life (healthcare) , pulse oximetry , population , overlap syndrome , oxygen saturation , asthma , anesthesia , nursing , environmental health , chemistry , organic chemistry , oxygen
Background: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) are both common disorders. Concomitant disease, overlap syndrome, is reported to cause a more severe condition. Aim: To describe a study designed to evaluate the prevalence of overlap syndrome in the general population, and further, to assess the impact of overlap syndrome on cardiovascular morbidity and health‐related quality of life. A secondary aim is to evaluate screening oxygen saturation (Sa02) by pulse oxymetry. Material and Method: From the last examination of the OLIN‐studies (Obstructive Lung Disease in Northern Sweden), cohorts I‐IV all subjects with FEV1 ≤ 50 percent predicted or Sa02 ≤ 93 percent predicted were identified (Phase 1). They are invited to a program including lab tests, spirometry, arterial blood gases, chest x‐ray, echocardiography, sleep studies and health‐related quality of life (HRQL) questionnaires. In Phase 2, a random sample of subjects reporting snoring as a problem ( n = 100) will be invited to a limited program above all including sleep studies and HRQL questionnaires; and in Phase 3, a random sample ( n = 100) will be invited to a similar program. Summary: The collection of data in Phase 1 is in progress and will be completed by the end of year 2007. Phase 2 will start year 2008. Please cite this paper as: Larsson L‐G and Lindberg A. Concomitant obstructive sleep apnea and chronic obstructive pulmonary disease: study design – the OLIN OSAS‐COPD study. The Clinical Respiratory Journal 2008; 2: 120–122.