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The effect of giving intra‐operative local anaesthetic (lidocaine 2% with 1:80 000 adrenaline) on post‐operative pain in adolescents having day‐case oral surgery to facilitate orthodontic treatment: A blinded, randomised controlled trial
Author(s) -
Murphy M.
Publication year - 2011
Publication title -
oral surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.156
H-Index - 11
eISSN - 1752-248X
pISSN - 1752-2471
DOI - 10.1111/j.1752-248x.2011.01133.x
Subject(s) - medicine , local anaesthetic , lidocaine , placebo , anesthesia , general anaesthetic , visual analogue scale , surgery , local anesthesia , general anaesthesia , local anesthetic , placebo group , alternative medicine , pathology
Aim: To elucidate the effect of giving local anaesthetic to adolescents having oral surgery carried out under day‐case general anaesthetic on their post‐operative pain. Materials and methods: Randomised, blinded, placebo‐controlled design. Sixty‐eight subjects aged 12–16 years randomly assigned to receive either a local anaesthetic (2% lidocaine with 1:80 000 adrenaline) or placebo (saline) infiltration at the surgical site before the start of surgery. Pain assessed by a research nurse using a visual analogue scale, firstly pre‐surgery and then at 30, 60 and 120 min post‐surgery. The time of post‐surgery rescue analgesia requirements also noted. Results: Mean pain scores were significantly less in the local anaesthetic group compared with the placebo group at 30 min post‐surgery ( P < 0.01) and at 60 min post‐surgery ( P < 0.01). There was no significant difference in mean pain scores at 120 min at which time the mean pain score in the placebo group had reduced to approach that of the local anaesthetic group. More subjects in the placebo group (21) required rescue analgesia compared with the local anaesthetic group (12). The mean time to rescue analgesia was significantly longer in the local anaesthetic group compared with the placebo group ( P = 0.04). Conclusions: Giving local anaesthetic infiltrations at the surgical site significantly reduced post‐operative pain in the early stages following oral surgery procedures carried out under general anaesthesia in adolescent subjects. It also reduced the need for post‐surgery analgesia and significantly increased the time from surgery to any such required analgesia.