Premium
IgG4‐related sclerosing sialadenitis in bilateral submandibular glands
Author(s) -
Kato K.,
Kawashiri S.,
Nakagawa K.,
Yamamoto E.,
Zen Y.
Publication year - 2009
Publication title -
oral surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.156
H-Index - 11
eISSN - 1752-248X
pISSN - 1752-2471
DOI - 10.1111/j.1752-248x.2009.01029.x
Subject(s) - sialadenitis , medicine , autoimmune pancreatitis , pathophysiology , pathology , infiltration (hvac) , pancreatitis , antibody , lesion , submandibular gland , igg4 related disease , salivary gland , disease , immunology , physics , thermodynamics
Chronic sclerosing sialadenitis (CSS) is a totally inflammatory lesion. In a 60‐year‐old male with CSS, serum immunoglobulin G (IgG) concentration was markedly increased and abundant infiltration of IgG4‐positive plasma cells was observed in the salivary glands. Autoimmune pancreatitis occurred during follow‐up. CSS and autoimmune pancreatitis would appear to show essentially the same pathophysiological mechanism. The abundance of IgG4‐positive plasma cells in the lesions would be useful for revealing other IgG4‐related disease in patients with CSS.