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Predictive utility of blood pressure, waist circumference and body mass index for metabolic syndrome in patients with schizophrenia in S ingapore
Author(s) -
Nurjono Milawaty,
Lee Jimmy
Publication year - 2013
Publication title -
early intervention in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.087
H-Index - 45
eISSN - 1751-7893
pISSN - 1751-7885
DOI - 10.1111/j.1751-7893.2012.00384.x
Subject(s) - waist , body mass index , metabolic syndrome , medicine , schizophrenia (object oriented programming) , circumference , predictive value , positive predicative value , receiver operating characteristic , blood pressure , population , predictive value of tests , gastroenterology , endocrinology , obesity , psychiatry , mathematics , geometry , environmental health
Aims This study aims to examine and compare the predictive utility of blood pressure ( BP ), waist circumference ( WC ) and body mass index ( BMI ), and to determine optimal cut‐off values in prediction of metabolic syndrome ( M et S ) in patients with chronic schizophrenia. Methods About 100 patients with chronic schizophrenia were recruited. BMI and BP were measured and laboratory tests to evaluate patients’ high‐density lipoprotein cholesterol, triglycerides and glucose levels were performed. Presence of M et S was examined according to AHA/NHLBI guidelines. Predictive utility of BP , WC and BMI was examined using receiver operating curve and discriminant indices were determined accordingly. Results Forty‐six (46%) patients were identified to have M et S . BMI of ≥23 kg m −2 was most accurate ( AUC = 0.83, P < 0.001), with sensitivity of 93.5%, specificity of 48.1%, positive predictive value of 60.6% and negative predictive value of 92.9% in identifying M et S . Conclusion This finding has immediate and significant clinical implications in the local population with schizophrenia.