
First‐Line Treatment for Hypertension
Author(s) -
SiuWa Chan Stewart,
Graham Colin A.,
Hudson Rainer Timothy
Publication year - 2012
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1751-7176.2011.00557.x
Subject(s) - medicine , thiazide , cardiology , blood pressure , vascular resistance , hemodynamics , adverse effect , diastole , intensive care medicine
Expert recommendations have until nowfocused on comparative analyses of cardiovascularoutcomes, efcacy in reducing blood pressure (BP),adverse effects, and cost. Essential hypertension can beclassied into distinct subtypes depending on the pri-mary hemodynamic derangement, which can either beincreased cardiac output (CO), as is more commonlyseen in the younger age group with sympathetic ner-vous system overactivity; or elevated systemic vascularresistance (SVR), as is seen in older patients.