Open AccessImprovements in Insulin Sensitivity and Muscle Blood Flow in Aerobic‐Trained Overweight‐Obese Hypertensive Patients Are Not Associated With Ambulatory Blood Pressure
Author(s) -
Waib Paulo H.,
Gonçalves Maria I.,
Barrile Silvia R.
Publication year - 2011
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1751-7176.2010.00393.x
Subject(s) - medicine , aerobic exercise , ambulatory blood pressure , blood pressure , insulin resistance , ambulatory , overweight , forearm , insulin , cardiology , homeostatic model assessment , vascular resistance , endocrinology , physical therapy , body mass index , surgery
To verify whether there are relationships between vascular and hormonal responses to aerobic training in hypertensive persons, sedentary hypertensive patients were randomized to an aerobic training or a callisthenic exercise group. The patients’ 24‐hour blood pressure, arterial compliance, forearm blood flow, and hormonal profile were evaluated at baseline and after 3‐month training protocols. Mean maximal oxygen consumption (VO 2 max) increased by 8% in the aerobic group ( P <.001), while no change was observed in the control group. There was a decrease in insulin resistance (homeostatic model assessment of insulin resistance, P =.039) and plasma cortisol ( P =.006) in the aerobic group only, that also demonstrated an increase in forearm blood flow ( P <.001) after training. No relationship was observed between change in blood pressure or change in body mass and other parameters. Aerobic training can promote a decrease in cardiovascular risk in hypertensive adults by improving vascular function and insulin resistance, despite no changes in ambulatory blood pressure after a 3‐month intervention. J Clin Hypertens (Greenwich). 2011;13:89–96. © 2010 Wiley Periodicals, Inc.