z-logo
open-access-imgOpen Access
Urine Albumin Excretion, Within Normal Range, Reflects Increasing Prevalence of Metabolic Syndrome in Patients With Essential Hypertension
Author(s) -
Vyssoulis Gregory,
Karpanou Eva,
Spanos Pangiotis,
Kyvelou StellaMaria,
Adamopoulos Dionysios,
Stefanadis Christodoulos
Publication year - 2010
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1751-7176.2010.00306.x
Subject(s) - medicine , microalbuminuria , albuminuria , metabolic syndrome , blood pressure , excretion , urine , diabetes mellitus , endocrinology , cardiology
J Clin Hypertens(Greenwich). 2010;12:597–602. © 2010 Wiley Periodicals, Inc. Microalbuminuria is a prognostic marker of cardiovascular disease and is related to metabolic syndrome (MetS). For this purpose, the authors examined the relationship of low grade albuminuria to MetS, using 4 current definitions and a MetS score. They studied 6650 consecutive, nondiabetic, hypertensive patients with normal microalbumin excretion. MetS was defined by Adult Treatment Panel III, American Heart Association, World Heart Organization, International Diabetes Federation criteria, and MetS Gruppo Italiano per lo Studio della Streptochinasi nell’Infarcto Miocardico (GISSI) score. Urine microalbumin concentration was measured after a 24‐hour urine collection by immunonephelometry. By all definitions, hypertensive patients with MetS had higher microalbumin levels. Significantly higher microalbumin levels were observed as the number of metabolic components rose. After adjustment for systolic blood pressure, the strength of this association was reduced to a nonsignificant level. Microalbumin levels, within normal range, are increased in patients with MetS, irrespective of the definition criteria.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here