Open AccessBlood Pressure Goals and Arterial Stiffness in Chronic Kidney Disease
Author(s) -
Liew YinPing,
Rafey Mohammed A.,
Allam Sridhar,
Arrigain Susana,
Butler Robert,
Schreiber Martin
Publication year - 2009
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1751-7176.2009.00096.x
Subject(s) - medicine , arterial stiffness , blood pressure , kidney disease , cardiology
The association of optimal blood pressure (BP) control and arterial stiffness was evaluated in 172 patients with chronic kidney disease. The authors compared the augmentation index (AIx) of patients who achieved a recommended BP goal (<130/80 mm Hg) with those who did not (≥130/80 mm Hg). The median age was 57 years, 60% were male, and 70% were Caucasian. One‐third of patients had achieved a BP goal of <130/80 mm Hg. AIx was significantly lower in patients who achieved BP goal than in those who did not (median AIx, 19% vs 23%; P =.04). AIx remained significantly lower in patients who achieved the BP goal, after adjusting for age, sex, and height (mean effect on AIx, −3.3%; 95% confidence interval, −6.1% to −0.4%; P =.03). Achievement of BP goal of <130/80 mm Hg in chronic kidney disease patients is associated with significantly lower AIx and may reflect a reduction in overall arterial stiffness.