Open AccessInsulin Therapy and Type 2 Diabetes: Management of Weight Gain
Author(s) -
McFarlane Samy I.
Publication year - 2009
Publication title -
the journal of clinical hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 67
eISSN - 1751-7176
pISSN - 1524-6175
DOI - 10.1111/j.1751-7176.2009.00063.x
Subject(s) - medicine , type 2 diabetes , weight gain , insulin , diabetes mellitus , intensive care medicine , endocrinology , body weight
The potential for insulin‐related weight gain in patients with type 2 diabetes presents a therapeutic dilemma and frequently leads to delays in the initiation of insulin therapy. It also poses considerable challenges when treatment is intensified. Addressing insulin‐related weight gain is highly relevant to the prevention of metabolic and cardiovascular consequences in this high‐risk population with type 2 diabetes. In addition to lifestyle changes (eg, diet and exercise) and available medical interventions to minimize the risk of weight gain with insulin treatment, familiarity with the weight gain patterns of different insulins may help deal with this problem. The use of basal insulin analogs may offer advantages over conventional human insulin preparations in terms of more physiologic time‐action profiles, reduced risk of hypoglycemia, and reduced weight gain.