Open AccessDobutamine Stress Cardiac Magnetic Resonance Imaging to Detect Myocardial Ischemia in Women
Author(s) -
Raman Subha V.,
Donnally Michael R.,
McCarthy Beth
Publication year - 2008
Publication title -
preventive cardiology
Language(s) - English
Resource type - Journals
eISSN - 1751-7141
pISSN - 1520-037X
DOI - 10.1111/j.1751-7141.2008.08243.x
Subject(s) - medicine , coronary artery disease , dobutamine , myocardial perfusion imaging , cardiology , stress testing (software) , ischemia , magnetic resonance imaging , radiology , stress echocardiography , cardiac catheterization , perfusion , hemodynamics , computer science , programming language
This study sought to evaluate dobutamine stress cardiac magnetic resonance imaging (DCMRI) in women with abnormal stress nuclear testing results. Women with findings on stress nuclear exams, including electrocardiography and/or perfusion, thought to require further evaluation with invasive coronary angiography were prospectively enrolled. Multiplane cine imaging was obtained at rest and at each stage of inotropic stress with atropine as needed to achieve target heart rate. DCMRI results were compared with stress nuclear and invasive cardiac catheterization results. Of 23 patients enrolled successfully, 22 completed DCMRI examination without complications. In all cases, DCMRI imaging demonstrated appropriate stress response with no ischemia despite abnormalities on stress nuclear testing. In the 18 patients who also underwent invasive coronary angiography, no significant obstructive disease was identified. DCMRI may be a useful alternative to stress nuclear examination in women; larger studies are warranted to determine its potential to more accurately predict obstructive coronary artery disease.