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Can the incidence of gastric cancer be reduced in the new century?
Author(s) -
Hu Ye,
Fang Jing Yuan,
Xiao Shu Dong
Publication year - 2013
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/j.1751-2980.2012.00647.x
Subject(s) - incidence (geometry) , medicine , cancer , gastroenterology , gastric adenocarcinoma , adenocarcinoma , mortality rate , helicobacter pylori , physics , optics
Gastric cancer ( GC ) is one of the most common cancers in the world. The incidence and mortality rate of GC vary among different countries. It is suggested that GC is the result of the interaction between H elicobacter pylori ( H. pylori ) infection and the genetic and environmental factors in the host. H . pylori infection is the trigger of intestinal gastric adenocarcinoma. The incidence of GC is highest in E ast A sia and E ast E urope, but much lower in A frica; however, H . pylori infection is commonly seen in A frica, which is known as the A frican enigma. The 5‐year survival of early GC is far better than that of advanced GC . A high detection rate of early GC could help us to conquer GC . A decreasing trend of GC incidence has been witnessed worldwide. With the improvement of living conditions and the achievements of scientific research, it seems possible that there will be a further reduction in the incidence of GC in the new century.