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Spectral Discrimination of Benign and Malignant Prostate Tissues––A Preliminary Report
Author(s) -
Masilamani Vadivel,
Rabah Danny,
AlSalhi Mohamad,
Trinka Vijmasi,
VijayaRaghavan Parthasarathy
Publication year - 2010
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.2010.00825.x
Subject(s) - autofluorescence , prostate , malignancy , nuclear magnetic resonance , pathology , spectroscopy , spectral line , resolution (logic) , chemistry , fluorescence , nuclear medicine , medicine , materials science , optics , physics , cancer , computer science , quantum mechanics , astronomy , artificial intelligence
In this preliminary report, benign ( n = 8) and malignant ( n = 5) prostate tissues, in vitro , have been taken through autofluorescence spectroscopy. Employing Stokes’ shift spectra and fluorescence emission spectra as tools of analysis, we were able to discriminate the two sets of tissues with sensitivity and specificity in excess of 85%. When the excised prostate chips were scanned with a spatial resolution of 1 mm, the epicenter of malignancy also could be delineated.