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Efficient Singlet Oxygen Generation by Luminescent 2‐(2′‐Thienyl)Pyridyl Cyclometalated Platinum(II) Complexes and Their Calixarene Derivatives
Author(s) -
Lai SiuWai,
Liu Ying,
Zhang Dong,
Wang Bin,
Lok ChunNam,
Che ChiMing,
Selke Matthias
Publication year - 2010
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.2010.00809.x
Subject(s) - singlet oxygen , pyridine , platinum , chemistry , luminescence , acetonitrile , quantum yield , phosphorescence , photochemistry , fluorescence , singlet state , calixarene , oxygen , yield (engineering) , medicinal chemistry , excited state , catalysis , molecule , materials science , organic chemistry , optoelectronics , physics , quantum mechanics , nuclear physics , metallurgy
Luminescent cyclometalated platinum(II) complexes, namely [Pt(Thpy)(PPh 3 )X] n + (HThpy = 2‐(2′‐thienyl)pyridine; X = Cl − ( 1 ), n = 0; X = CH 3 CN ( 2 ), pyridine ( 3 ), n = 1) and [Pt(Thpy)(HThpy)Y] n + (Y = Cl − ( 4 ), n = 0; Y = pyridine ( 5 ), n = 1), exhibit structured emission with peak maximum at ∼556 and 598 nm in degassed acetonitrile and with emission quantum yield and lifetime of up to 0.38 and 26 μs, respectively. These complexes are efficient photosensitizers of singlet oxygen with yields up to >90%. Complex 5 exhibited photocytotoxicity towards cancer cells and fluorescence microscopic images of cells incubated with 5 reveal substantial uptake at the nucleus and mitochondria.