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Ultrasonic Modulation of Scattered Light in Turbid Media and a Potential Novel Tomography in Biomedicine
Author(s) -
Wang Lihong V.
Publication year - 1998
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1998.tb05163.x
Subject(s) - optics , ultrasonic sensor , signal (programming language) , laser , modulation (music) , materials science , ultrasound , raster scan , light field , detector , physics , acoustics , computer science , programming language
Ultrasonic modulation of scattered laser light was used to image objects buried in tissue‐simulating turbid media. The ultrasonic wave focused into the turbid media modulated the laser light passing through the ultrasonic field. The modulated laser light collected by a photomultiplier tube reflected primarily the local mechanical and optical properties in the zone of ultrasonic modulation. A raster scanning over a heterogeneous turbid medium yielded an image of the medium based on the ultrasound‐modulated optical signal. The detectability of modulated signal was estimated using diffusion theory. The dependence of the modulated signal on the off‐axis distance of the detector from the optic axis and on the amplitude of ultrasound was studied. The mechanisms of ultrasonic modulation of scattered light are discussed. A theory based on the field autocorrelation function is reviewed as well.