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Effect of Glucose on Photodynamic Action of Methylene Blue in Escherichia coli Cells
Author(s) -
Capella Márcia,
Coelho Ana Maria,
Menezes Salatiel
Publication year - 1996
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1996.tb02443.x
Subject(s) - methylene blue , escherichia coli , chemistry , adenosine , methylene , sucrose , biochemistry , medicinal chemistry , catalysis , gene , photocatalysis
The results of this work show that the resistance of Escherichia coli cells to the photodynamic action of methylene blue is increased by the addition of glucose to the media in which they are grown. It is postulated that the increased resistance may be due to lowered retention of the dye by cells grown in the presence of glucose, leading to the diminution in DNA damage revealed in the alkaline sucrose gradients. The role of cyclic adenosine‐monophosphate in the protective action of glucose is discussed.