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EARLY ALTERATIONS OF ACTIN IN CULTURED HUMAN KERATINOCYTES AND FIBROBLASTS EXPOSED TO LONG‐WAVELENGTH RADIATIONS. POSSIBLE INVOLVEMENT IN THE UVA‐INDUCED PERTURBATIONS OF ENDOCYTOTIC PROCESSES
Author(s) -
DjavaheriMergny M.,
Pieraggi M. T.,
Mazière C.,
Santus R.,
Lageron A.,
Salvayre R.,
Dubertret L.,
Mazière J. C.
Publication year - 1994
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1994.tb05000.x
Subject(s) - microbiology and biotechnology , actin , biology , biophysics
Exposure of cultured MRC5 human fibroblasts or NCTC 2544 human keratinocytes to mild doses of ultraviolet A (UVA: 320‐400 nm) radiations markedly decreased the actin reactivity with fluorescein‐labeled phalloidin. This indicates a change in the degree of poly merization of actin and thus in the organization of actin filaments. Such a phenomenon might be involved in the previously reported UVA‐induced inhibition of specific and nonspecific endocytotic processes.