Premium
TANNING SALON EXPOSURE SUPPRESSION OF DNA REPAIR CAPACITY AND MITOGEN‐INDUCED DNA SYNTHESIS
Author(s) -
LARCOM L. L.,
MORRIS T. E.,
SMITH M. E.
Publication year - 1991
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1991.tb03663.x
Subject(s) - carcinogen , dna repair , dna damage , dna synthesis , dna , immunology , biology , cancer research , medicine , genetics
— Mitogen responsiveness and the capacity to repair genetic damage were measured in lymphocytes collected from young, healthy, adult Caucasians immediately before exposure in commercial tanning salons and again 24 h after exposure. For every individual studied, tanning exposure produced significant inhibition of phytohemagglutinin‐induced mitogenesis or of the ability to repair DNA lesions by unscheduled DNA synthesis. The results imply that such exposure could: (1) pose a significant hazard for individuals who are already immunosuppressed (e. g. cancer patients, AIDS patients or carriers of latent HIV) and (2) increase the carcinogenic effects of environmental mutagens.