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TUMORIGENESIS BY A LONG WAVELENGTH UV‐A SOURCE
Author(s) -
Sterenborg H. J. C. M.,
Leun J. C.
Publication year - 1990
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1990.tb01718.x
Subject(s) - hairless , wavelength , carcinogenesis , scratching , radiation , light source , chemistry , nuclear medicine , optoelectronics , optics , materials science , medicine , physics , cancer , biochemistry , composite material
— Albino hairless mice (Skh‐hrl) were exposed daily to radiation from a high‐power long wavelength UV‐A source (wavelengths longer than 340 nm). The irradiations lasted 2 h per day. The daily dose was 220 kJ/m 2 . Heavy scratching marks were observed in 13 out of 48 animals. However during the experiment 31 of the animals developed tumors of 1 mm or larger before any scratching was observed. The median induction time was 265 days for 1 mm tumors.