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THE DIRECT OBSERVATION OF A PSORALEN‐THYMINE UVA INDUCED SOLID‐STATE CYCLOADDITION REACTION PRODUCT BY SINGLE‐CRYSTAL x‐RAY DIFFRACTOMETRY
Author(s) -
PFLUGER C. E.,
OSTRANDER R. L.
Publication year - 1989
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1989.tb09182.x
Subject(s) - psoralen , thymine , chemistry , cycloaddition , solid state , crystallography , single crystal , x ray , ring (chemistry) , diffraction , crystal structure , x ray crystallography , dna , stereochemistry , photochemistry , organic chemistry , catalysis , optics , biochemistry , physics
— Single‐crystal x‐ray diffraction methods have been used to directly observe and simultaneously determine the molecular structure of the UVA induced cis‐syn photocycloaddition product in a partially photolyzed single crystal of a psoralen(pyrone ring side)‐DNA(thymine) interaction model compound, 1 ‘‐(8‐oxypsoralen)‐8’(thym‐l“yl)3‘,6’‐dioxaoctane.