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MECHANISTIC STUDIES OF THE PHOTOREACTION OF FLAVIN WITH N, N‐DIMETHYLPROPARGYLAMINE
Author(s) -
FRANKE JÜRGEN,
OTT ULRICH,
KRAMER HORST E. A.,
TRABER RAINER H.
Publication year - 1989
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1989.tb04086.x
Subject(s) - flavin group , flash photolysis , photochemistry , chemistry , adduct , radical , yield (engineering) , riboflavin , oxygen , photodissociation , mechanism (biology) , kinetics , reaction rate constant , organic chemistry , biochemistry , materials science , enzyme , physics , quantum mechanics , metallurgy , philosophy , epistemology
Both photoexcited free flavin and protein‐bound flavin react with N, N‐dimethylpropargyla‐mine (DMPA) to yield dihydroflavin‐adducts which are not reoxidizable by oxygen. The mechanism of the photoreaction was reinvestigated by flash photolysis and continuous illumination experiments. We suggest that a mechanism occurs in which a flavosemiquinone and a DMPA radical result in the first photoinduced reaction. The flavin‐DMPA adducts are then formed by combinations of the two radicals.