Premium
BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES‐X. SYNTHESES AND ANALYSES OF SULFONATED PHTHALOCYANINES
Author(s) -
Ali Hasrat,
Langlois Réjean,
Wagner J. Richard,
Brasseur Nicole,
Paquette Benoit,
Lier Johan E.
Publication year - 1988
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1988.tb02769.x
Subject(s) - chemistry , phthalocyanine , reagent , sulfonate , condensation , methanol , aqueous solution , molecule , condensation reaction , ring (chemistry) , organic chemistry , chromatography , catalysis , physics , thermodynamics , sodium
— Synthetic methods to obtain selectively sulfonated metallo phthalocyanines are compared. Both condensation and direct sulfonation procedures lead to mixtures of mono‐ to tetrasulfonated products which are resolved by reverse phase liquid chromatography in buffered aqueous‐methanol. The proportion of sulfonated derivatives is examined as a function of the starting reagents in the case of the condensation method, and as a function of the temperature and reaction time in the case of the direct sulfonation procedure. The number of sulfonate groups per phthalocyanine molecule is determined by oxidative degradation of the phthalocyanine ring followed by quantitative chromatographic analysis of the sulfophthalamide and phthalamide fragments.