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PHOTOPHYSICAL PROPERTIES OF A CHLORIN, A POTENT SENSITIZER FOR PHOTOCHEMOTHERAPY
Author(s) -
Brault Daniel,
VeverBizet Christine,
Rougée Michel,
Bensasson René
Publication year - 1988
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1988.tb02705.x
Subject(s) - singlet oxygen , photosensitizer , photochemistry , chlorin , chemistry , radical , singlet state , photodynamic therapy , oxygen , absorption (acoustics) , porphyrin , molecule , materials science , excited state , organic chemistry , physics , nuclear physics , composite material
— Photophysical and photodynamic properties of a ehlorin type molecule derived from hydroxyethylvinyldeuteroporphyrin are presented. It photosensitizes singlet oxygen production as efficiently as mesotetraphenylporphin. The high absorptions of both its ground and triplet states in the red (660 nm) make it a potent photosensitizer which might act not only by photo‐oxidation via singlet oxygen but also by radicals produced via sequential biphotonic absorption.